Nobiletin protects against alcohol-induced mitochondrial dysfunction and liver injury by regulating the hepatic NRF1-TFAM signaling pathway
Our study elucidates the involvement of the NRF1-TFAM signaling pathway in the protective mechanism of NOB against chronic-plus-binge alcohol consumption-induced mitochondrial dysfunction and liver injury, suggesting NOB supplementation as a potential therapeutic strategy for ALD.
Authors
- Xiaolong Yu (ORCID: https://orcid.org/0000-0002-0734-3562)
- Xiao-Qing Tong
- Songtao Li (ORCID: https://orcid.org/0000-0002-2926-673X)
- Xiaoyan Zhang (ORCID: https://orcid.org/0000-0002-0523-4581)
- Dan Lü (ORCID: https://orcid.org/0000-0002-0789-4655)
- Aiping Huang
Institutions
- Zhejiang Chinese Medical University (CN)
- Zhejiang Hospital (CN)
- Blood Center of Zhejiang Province (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1080/13510002.2024.2395779
- Citations
- 6
- Primary Topic
- Bioactive Compounds in Plants
- Type
- article
- Field-Weighted Citation Impact
- 3.60
Funders
- Zhejiang Traditional Chinese Medicine Administration
- Science and Technology Department of Zhejiang Province
- Science and Technology Program of Zhejiang Province