A Pharmacologic Evaluation of Buprenorphine in Pregnancy and the Postpartum Period
Pregnant people require a higher dose of buprenorphine to achieve concentrations comparable to nonpregnant people. There is a temporal relationship between the plasma buprenorphine concentration and the pharmacodynamic markers of pupillary diameter, COWS, and craving scores. An average plasma concentration of ~1 ng/mL was associated with the lowest level of COWS and craving scores.
Authors
- Raman Venkataramanan
- Steve N. Caritis (ORCID: https://orcid.org/0000-0002-2169-0712)
Institutions
- University of Pittsburgh (US)
- Magee-Womens Hospital (US)
Publication Details
- Journal
- Journal of Addiction Medicine
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1097/adm.0000000000001380
- Citations
- 1
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development