Dual-species proteomics and targeted intervention of animal-pathogen interactions

Our work provides a novel SILAC-based proteomics method that can simultaneously evaluate host and microbe proteomes, with future applications in higher host organisms and other microbial species. It also provides insights into the mechanisms dictating host-microbe interactions, offering novel strategies for anti-infective therapy.

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Publication Details

Journal
Journal of Advanced Research
Published
2024-09-02
DOI
https://doi.org/10.1016/j.jare.2024.08.038
Citations
6
Primary Topic
Bacteriophages and microbial interactions
Type
article
Field-Weighted Citation Impact
2.75

Funders

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article

Dual-species proteomics and targeted intervention of animal-pathogen interactions

Bee Luan Khoo, Chengqian Zhang, Piliang Hao, Yang Sylvia Liu et al.
6 citations
Journal of Advanced Research
Bacteriophages and microbial interactions
2.75
article

Dual-species proteomics and targeted intervention of animal-pathogen interactions

Bee Luan Khoo, Chengqian Zhang, Piliang Hao, Yang Sylvia Liu, Song Lin Chua
article en
6 citations

Abstract

Our work provides a novel SILAC-based proteomics method that can simultaneously evaluate host and microbe proteomes, with future applications in higher host organisms and other microbial species. It also provides insights into the mechanisms dictating host-microbe interactions, offering novel strategies for anti-infective therapy.

Journal of Advanced ResearchVol. 73
Hong Kong Polytechnic University (HK), City University of Hong Kong (HK), ShanghaiTech University (CN), City University of Hong Kong, Shenzhen Research Institute (CN)
Northwest University, Hong Kong Polytechnic University, National Institutes of Health, Health and Medical Research Fund
Zero hunger
Openalex Percentile: Top 10%
Bacteriophages and microbial interactions
2.75
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Dual-species proteomics and targeted intervention of animal-pathogen interactions — Bee Luan Khoo, Chengqian Zhang, et al. · Journal of Advanced Research (2024) | TGRS Research Map | TGRS