Salidroside alleviates simulated microgravity-induced bone loss by activating the Nrf2/HO-1 pathway
These findings indicate that salidroside has great potential for treating space-related bone loss in astronauts and suggest that Nrf2/HO-1 is a viable target for counteracting microgravity-induced bone damage.
Authors
- Zhuan Zuo
- Yongsheng Ma (ORCID: https://orcid.org/0000-0002-1642-1585)
- Meng Tong (ORCID: https://orcid.org/0000-0003-4832-2490)
- Xiwei Zheng
- Yuliang Liu
- Nan Wang (ORCID: https://orcid.org/0009-0003-9735-4314)
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- First Hospital of Xi'an (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1186/s13018-024-05030-1
- Citations
- 6
- Primary Topic
- Spaceflight effects on biology
- Type
- article
- Field-Weighted Citation Impact
- 1.96