Integrated ultrasensitive metabolomics and single-cell transcriptomics identify crucial regulators of sheep oocyte maturation and early embryo development in vitro
Together, these analyses identified key metabolites that promote ovine oocyte maturation and early embryo development, while also providing a new viewpoint to improve clinical applications such as oocyte maturation or embryo culture.
Authors
- Bo Pan (ORCID: https://orcid.org/0000-0002-0984-2058)
- Gongxue Jia (ORCID: https://orcid.org/0000-0002-0810-3210)
- JiangFeng Ye
- Jianpeng Qin (ORCID: https://orcid.org/0000-0002-4076-9776)
- Guangbin Zhou (ORCID: https://orcid.org/0000-0002-4493-8311)
- Luyao Zhang (ORCID: https://orcid.org/0009-0008-5258-1413)
- QiEn Yang
- QiuXia Liang
- Kunlin Du
Institutions
- Chinese Academy of Sciences (CN)
- Sichuan Agricultural University (CN)
- Xinjiang Institute of Ecology and Geography (CN)
- Ministry of Agriculture and Rural Affairs (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1016/j.jare.2024.08.040
- Citations
- 10
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 5.43
Funders
- Tsinghua University
- Sichuan Agricultural University
- National Key Research and Development Program of China