Macrophage polarization in human periapical lesions in relation to histopathological diagnosis, clinical features and lesion volume: An ex vivo study
Periapical granulomas are characterized by a M2-dominant macrophage polarization, while radicular cysts have significantly higher M1 macrophages. The higher degree of M1 macrophage polarization was significantly correlated with larger volume and higher CBCTPAVI scores of overall periapical lesion and periapical granuloma.
Authors
- Chootima Ratisoontorn (ORCID: https://orcid.org/0000-0001-9477-1540)
- Kittipong Dhanuthai (ORCID: https://orcid.org/0000-0001-7922-8582)
- Soranun Chantarangsu (ORCID: https://orcid.org/0000-0002-3400-5585)
- Anchana Panichuttra
- Phonkit Sinpitaksakul (ORCID: https://orcid.org/0000-0002-3554-0969)
- Supanant Visarnta
Institutions
- Chulalongkorn University (TH)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1111/iej.14138
- Citations
- 5
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.47