Hepatocellular carcinoma and AIM2: Therapeutic potential through regulation of autophagy and macrophage polarization
The findings underscore AIM2's crucial function in modulating major biological processes in HCC, pointing to its potential as a therapeutic target. This study inaugurally demonstrated that AIM2 activates autophagy and influences macrophage polarization, playing a role in liver cancer progression.
Authors
- Shumin Ma (ORCID: https://orcid.org/0000-0001-6361-9706)
- Jinhong Yu
- Cuiyun Wang
- Wenjun Du (ORCID: https://orcid.org/0000-0002-6753-5910)
- Xiaoyan Liu (ORCID: https://orcid.org/0000-0002-1732-5923)
- Qiang Li (ORCID: https://orcid.org/0000-0002-8667-4676)
- Cheng Li (ORCID: https://orcid.org/0009-0006-9374-5707)
- Shuangshuang Xie
Institutions
- Shanghai Public Health Clinical Center (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/iid3.70002
- Citations
- 4
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.55