Exposure to organophosphate ester flame retardants and plasticizers and associations with preeclampsia and blood pressure in pregnancy
We observed null associations between OPE metabolites and preeclampsia, but some positive and some inverse associations with blood pressure in pregnancy. While our study was well-designed to assess associations with blood pressure, future studies with a larger number of preeclampsia cases may be better poised to investigate the association between OPE metabolites and phenotypes of this heterogenous hypertensive disorder of pregnancy.
Authors
- María Ospina (ORCID: https://orcid.org/0000-0003-2682-4510)
- Barrett M. Welch (ORCID: https://orcid.org/0000-0002-1304-2272)
- Paige A. Bommarito (ORCID: https://orcid.org/0000-0002-4794-3570)
- John D. Meeker (ORCID: https://orcid.org/0000-0001-8357-5085)
- Kelly K. Ferguson (ORCID: https://orcid.org/0000-0001-8467-3250)
- Thomas F. McElrath (ORCID: https://orcid.org/0000-0003-0857-0107)
- Amir J. Lueth (ORCID: https://orcid.org/0000-0002-2373-9372)
- David E. Cantonwine (ORCID: https://orcid.org/0000-0002-3706-9584)
- Antonia M. Calafat (ORCID: https://orcid.org/0000-0002-9796-7482)
- Danielle R. Stevens (ORCID: https://orcid.org/0000-0002-4321-8355)
Institutions
- Brigham and Women's Hospital (US)
- Centers for Disease Control and Prevention (US)
- University of Nevada, Reno (US)
- Harvard University (US)
- University of Michigan (US)
- National Center for Environmental Health (US)
- National Institute of Environmental Health Sciences (US)
Publication Details
- Journal
- Environmental Research
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1016/j.envres.2024.119910
- Citations
- 6
- Primary Topic
- Toxic Organic Pollutants Impact
- Type
- article
- Field-Weighted Citation Impact
- 1.89
Funders
- National Institutes of Health
- National Institute of Environmental Health Sciences