Cleavage and polyadenylation factors are potential regulators of adipogenesis

We observed that while the RNA expression of these proteins is unchanged during differentiation, the protein levels of some subunits do change, including a decrease in levels of CPSF73, the nuclease that cuts at the poly(A) site. However, overexpression of CPSF73 alone does not affect the efficiency and rate of differentiation.

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Publication Details

Journal
BMC Research Notes
Published
2024-09-02
DOI
https://doi.org/10.1186/s13104-024-06908-3
Primary Topic
RNA Research and Splicing
Type
article
Field-Weighted Citation Impact
0.00

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article

Cleavage and polyadenylation factors are potential regulators of adipogenesis

Claire Moore, Salwa Mohd Mostafa
BMC Research Notes
RNA Research and Splicing
article

Cleavage and polyadenylation factors are potential regulators of adipogenesis

Claire Moore, Salwa Mohd Mostafa
article en

Abstract

We observed that while the RNA expression of these proteins is unchanged during differentiation, the protein levels of some subunits do change, including a decrease in levels of CPSF73, the nuclease that cuts at the poly(A) site. However, overexpression of CPSF73 alone does not affect the efficiency and rate of differentiation.

BMC Research NotesVol. 17(1)
Tufts University (US)
National Institutes of Health
Openalex Percentile: Top 87%
RNA Research and Splicing
DOIOpen Access PDFOpenAlex
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Cleavage and polyadenylation factors are potential regulators of adipogenesis — Claire Moore, Salwa Mohd Mostafa · BMC Research Notes (2024) | TGRS Research Map | TGRS