Impact of Phenylketonuria on the Serum Metabolome and Plasma Lipidome: A Study in Early-Treated Patients
This study provides insight into the metabolic phenotype of PKU patients. Additional studies are required to establish whether the observed changes result from PKU itself, diet, and/or an unknown reason.
Authors
- Francjan J. van Spronsen (ORCID: https://orcid.org/0000-0002-3773-1929)
- Stephan J. L. Bakker (ORCID: https://orcid.org/0000-0003-3356-6791)
- Ron A. Wevers (ORCID: https://orcid.org/0000-0003-2278-9746)
- Udo F. H. Engelke (ORCID: https://orcid.org/0000-0002-0980-238X)
- Pim de Blaauw
- Annemiek M. J. van Wegberg (ORCID: https://orcid.org/0000-0002-9402-4833)
- J Groen (ORCID: https://orcid.org/0000-0003-3087-8087)
- Karlien L. M. Coene (ORCID: https://orcid.org/0000-0001-9873-1458)
- J. C. van der Weerd
- Margaretha Rebecca Heiner-Fokkema (ORCID: https://orcid.org/0000-0002-3477-0770)
- Theo Boer
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- University of Groningen (NL)
- University Medical Center (US)
- Radboud University Medical Center (NL)
- Máxima Medisch Centrum (NL)
Publication Details
- Journal
- Metabolites
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3390/metabo14090479
- Citations
- 7
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.67
Funders
- Servier