Triglyceride Levels, Alirocumab Treatment, and Cardiovascular Outcomes After an Acute Coronary Syndrome
Among patients with recent ACS on optimized statin therapy, baseline triglycerides was associated with cardiovascular risk. However, the reduction in triglycerides with alirocumab did not contribute to its clinical benefit. (ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab; NCT01663402).
Authors
- Patrick M. Moriarty (ORCID: https://orcid.org/0000-0001-5548-4493)
- Philippe Gabríel Steg (ORCID: https://orcid.org/0000-0001-6896-2941)
- J. Wouter Jukema (ORCID: https://orcid.org/0000-0002-3246-8359)
- Andrzej Budaj (ORCID: https://orcid.org/0000-0002-6395-2098)
- Deepak L. Bhatt (ORCID: https://orcid.org/0000-0002-1278-6245)
- Rafael Díaz (ORCID: https://orcid.org/0000-0003-2181-9579)
- Róbert Gábor Kiss (ORCID: https://orcid.org/0000-0003-0514-7530)
- Robert Pordy (ORCID: https://orcid.org/0000-0002-8001-6795)
- Shaun G. Goodman (ORCID: https://orcid.org/0000-0001-8068-2440)
- Vera Bittner (ORCID: https://orcid.org/0000-0001-9456-850X)
- Gregory P. Geba (ORCID: https://orcid.org/0000-0001-8936-748X)
- Robert A. Harrington (ORCID: https://orcid.org/0000-0001-5450-8676)
- Gregory G. Schwartz (ORCID: https://orcid.org/0000-0003-2954-0695)
- Michael Szarek (ORCID: https://orcid.org/0000-0002-0046-0264)
- Garen Manvelian (ORCID: https://orcid.org/0000-0002-5491-1032)
- Weiming Du
- Sergio Fazio (ORCID: https://orcid.org/0000-0002-8145-8034)
- Doron Zahger
- Harvey D. White
- Andreas M. Zeiher
- Michel Scemama
Institutions
- Semmelweis University (HU)
- Goethe University Frankfurt (DE)
- Ben-Gurion University of the Negev (IL)
- St. Michael's Hospital (CA)
- Mount Sinai Health System (US)
- State University of New York (US)
- University of Alberta (CA)
- Inserm (FR)
- SUNY Downstate Health Sciences University (US)
- University of Toronto (CA)
- Regeneron (United States) (US)
- Université Paris Cité (FR)
- Leiden University Medical Center (NL)
- Sanofi (France) (FR)
- University of Alabama at Birmingham (US)
- Greenlane Clinical Centre (NZ)
- Assistance Publique – Hôpitaux de Paris (FR)
- Netherlands Heart Institute (NL)
- Canadian VIGOUR Centre (CA)
- University of Kansas Medical Center (US)
- Meridian Clinical Research (US)
- Instituto Cardiovascular de Rosario (AR)
- Center for Clinical Research (United States) (US)
- Grochowski Hospital (PL)
- University of Colorado Denver (US)
- Stanford University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of the American College of Cardiology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.jacc.2024.06.035
- Citations
- 13
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 7.45
Funders
- Regeneron Pharmaceuticals