Dynamic Peripheral T-Cell Analysis Identifies On-Treatment Prognostic Biomarkers of Atezolizumab plus Bevacizumab in Hepatocellular Carcinoma
These findings highlight the potential of dynamic changes in CD8<sup>+</sup> T cells as an on-treatment prognostic biomarker. Our study underscores the value of peripheral blood profiling as a noninvasive and practical method for predicting the clinical outcomes of AB treatment in patients with HCC.
Authors
- Min Woo Kang
- Ji Won Han (ORCID: https://orcid.org/0000-0003-1456-1450)
- Pil Soo Sung (ORCID: https://orcid.org/0000-0002-5780-9607)
- Si Hyun Bae (ORCID: https://orcid.org/0000-0003-1727-7842)
- Jeong Won Jang (ORCID: https://orcid.org/0000-0003-3255-8474)
- Soon Kyu Lee (ORCID: https://orcid.org/0000-0003-1865-8225)
- Young Chul Yoon (ORCID: https://orcid.org/0000-0002-5341-2370)
- Hyun Yang (ORCID: https://orcid.org/0000-0001-6588-9806)
- Jung Hyun Kwon (ORCID: https://orcid.org/0000-0002-5484-5864)
- Jae-Sung Yoo (ORCID: https://orcid.org/0009-0005-7875-6486)
- Ji Hoon Kim
- Jong Young Choi
- Deok Hwa Seo
- Eun Ji Jang
- Soon Woo Nam
- Hee Sun Cho (ORCID: https://orcid.org/0009-0001-6587-5081)
Institutions
- The Catholic University of Korea Incheon St. Mary's Hospital (KR)
- The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Liver Cancer
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1159/000541181
- Citations
- 5
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Seoul St. Mary's Hospital, Catholic University of Korea
- Incheon St. Mary's Hospital, Catholic University of Korea