Weight Loss Differentially Impacts Sex Hormones in Women and Men With Type 2 Diabetes: Look AHEAD Sex Hormone Study
Weight loss in T2D resulted in sex hormone changes, which varied by sex and were mediated by changes in waist circumference. Changes in sex hormones due to weight loss in T2D should be considered in the context of an individual's health risks, including cardiovascular conditions, bone health, menopausal symptoms, and cognitive function.
Authors
- Wendy L. Bennett (ORCID: https://orcid.org/0000-0001-9828-0706)
- Erin D. Michos (ORCID: https://orcid.org/0000-0002-5547-5084)
- Mark Woodward (ORCID: https://orcid.org/0000-0001-9800-5296)
- Rita Rastogi Kalyani (ORCID: https://orcid.org/0000-0002-1530-6884)
- Jun Yang (ORCID: https://orcid.org/0000-0002-9401-3528)
- Greg Ellis
- Jianqiao Ma (ORCID: https://orcid.org/0009-0009-5001-1422)
- Allen D. Everett (ORCID: https://orcid.org/0000-0002-5559-6708)
- Nazia Syed (ORCID: https://orcid.org/0000-0002-0396-9357)
- David R. Graham (ORCID: https://orcid.org/0000-0001-5454-4108)
- Jeanne M. Clark (ORCID: https://orcid.org/0000-0003-1194-0092)
- Dhananjay Vaidya (ORCID: https://orcid.org/0000-0002-7164-1601)
- Jiahuan He (ORCID: https://orcid.org/0000-0003-2965-3331)
Institutions
- Johns Hopkins University (US)
- The George Institute for Global Health (GB)
- Johns Hopkins Medicine (US)
- UNSW Sydney (AU)
- Johns Hopkins All Children's Hospital (US)
- The George Institute for Global Health (AU)
- Imperial College London (GB)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1210/clinem/dgae584
- Citations
- 12
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 4.29
Funders
- National Institutes of Health