Joint and interactive associations of body mass index and genetic factors with cardiovascular disease: a prospective study in UK Biobank
BMI and genetic factors jointly and interactively contribute to incident CVD, especially among participants with high genetic risk. These findings have public health implications for identifying populations more likely to have cardiovascular benefit from weight loss interventions.
Authors
- Yaqian Wu (ORCID: https://orcid.org/0000-0002-8337-4117)
- Yang Zhao (ORCID: https://orcid.org/0000-0002-5972-1000)
- Zihang Zhong
- Chunjian Li (ORCID: https://orcid.org/0000-0002-2359-7570)
- Jingwei Wu (ORCID: https://orcid.org/0000-0003-1003-619X)
- Senmiao Ni (ORCID: https://orcid.org/0000-0003-4290-1926)
- Jianling Bai (ORCID: https://orcid.org/0000-0002-9845-5198)
- Jiong Li (ORCID: https://orcid.org/0000-0003-1125-026X)
- Ruyu Huang
- Rui Geng
- Dongfang You
- Tao Chen (ORCID: https://orcid.org/0009-0005-4814-0664)
- Xinxin Kong
Institutions
- Jiangsu Province Hospital (CN)
- University of York (GB)
- Nanjing Medical University (CN)
- Temple University (US)
Publication Details
- Journal
- BMC Public Health
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1186/s12889-024-19916-6
- Citations
- 4
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.20
Funders
- National Natural Science Foundation of China
- Qinglan Project of Jiangsu Province of China