Formulation Strategy and An Overview of Nano-Structured Lipid Carrier-Based Topical Gel as a Novel Drug Delivery System

Nano-Structured Lipid Carriers (NLCs) are improved Solid Lipid Nanoparticles (SLNs) that recover the permanency and capacity of drug payload. There are 3 different types of NLCs which have been anticipated. The aforementioned Lipid Nano Particles (LNPs) possess possible tenders in drug delivery systems, cosmeceuticals, clinical research and many others. Here, we highlight the structure, ingredients, different manufacturing techniques and analysis of NLCs which are rudiments in formulating a unique drug delivery system. These types of formulations are therapeutically advantageous like skin hydration, occlusion and improved bioavailability as well as skin targeting. In this article, we have also discussed the features, and novelty of NLCs, different advantages as promising assistance in topical drug delivery systems, shortcomings and utilisations of LNPs by concentrating on NLCs.

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Publication Details

Journal
Pharmaceutical Nanotechnology
Published
2024-09-02
DOI
https://doi.org/10.2174/0122117385325593240820044758
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
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article

Formulation Strategy and An Overview of Nano-Structured Lipid Carrier-Based Topical Gel as a Novel Drug Delivery System

Anindya Bose, Ujjwal Kumar Biswas
Pharmaceutical Nanotechnology
Advancements in Transdermal Drug Delivery
article

Formulation Strategy and An Overview of Nano-Structured Lipid Carrier-Based Topical Gel as a Novel Drug Delivery System

Anindya Bose, Ujjwal Kumar Biswas
article en

Abstract

Nano-Structured Lipid Carriers (NLCs) are improved Solid Lipid Nanoparticles (SLNs) that recover the permanency and capacity of drug payload. There are 3 different types of NLCs which have been anticipated. The aforementioned Lipid Nano Particles (LNPs) possess possible tenders in drug delivery systems, cosmeceuticals, clinical research and many others. Here, we highlight the structure, ingredients, different manufacturing techniques and analysis of NLCs which are rudiments in formulating a unique drug delivery system. These types of formulations are therapeutically advantageous like skin hydration, occlusion and improved bioavailability as well as skin targeting. In this article, we have also discussed the features, and novelty of NLCs, different advantages as promising assistance in topical drug delivery systems, shortcomings and utilisations of LNPs by concentrating on NLCs.

Pharmaceutical NanotechnologyVol. 13(3)
Siksha O Anusandhan University (IN)
Good health and well-being
Openalex Percentile: Top 89%
Advancements in Transdermal Drug Delivery
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Formulation Strategy and An Overview of Nano-Structured Lipid Carrier-Based Topical Gel as a Novel Drug Delivery System — Anindya Bose, Ujjwal Kumar Biswas · Pharmaceutical Nanotechnology (2024) | TGRS Research Map | TGRS