The ADNI4 Digital Study: A novel approach to recruitment, screening, and assessment of participants for AD clinical research
A total of 654 participants enrolled in a digital cohort to facilitate ADNI4 recruitment. Culturally-informed digital ads aided enrollment of underrepresented populations. From those enrolled, 42% were from underrepresented ethnocultural and educational groups. Digital screening tools indicate > 50% of participants likely cognitively impaired. Completion rates and assessment performance vary by ethnocultural group and education.
Authors
- Magda Korecka
- Jack Weston (ORCID: https://orcid.org/0000-0001-5344-7840)
- Winnie Kwang
- Emil Fristed (ORCID: https://orcid.org/0000-0002-9590-7275)
- Catherine Conti
- Juliet Fockler
- Miriam T. Ashford (ORCID: https://orcid.org/0000-0003-4045-6435)
- Mónica Rivera Mindt (ORCID: https://orcid.org/0000-0001-6350-321X)
- Danielle Harvey
- Bruce Albala
- Ronald Carl Petersen (ORCID: https://orcid.org/0000-0002-8178-6601)
- Diana Truran Sacrey
- Derek Flenniken
- Laurel Beckett (ORCID: https://orcid.org/0000-0002-2418-9843)
- Edward B. Lee (ORCID: https://orcid.org/0000-0002-4589-1180)
- Melanie J. Miller (ORCID: https://orcid.org/0000-0002-7189-1109)
- Rachel L. Nosheny (ORCID: https://orcid.org/0000-0003-4995-8319)
- Caroline Skirrow (ORCID: https://orcid.org/0000-0001-8692-7787)
- Yang Wan (ORCID: https://orcid.org/0009-0003-8542-0900)
- Ozioma C. Okonkwo (ORCID: https://orcid.org/0009-0009-8764-811X)
- Michael W. Weiner
- Paul Aisen
- Adam Diaz
- Sarah Tomaszewski Farias (ORCID: https://orcid.org/0009-0009-8969-3387)
- Yi‐Ju Li (ORCID: https://orcid.org/0000-0001-6996-4834)
Institutions
- University of Southern California (US)
- Autism Research Institute (US)
- San Francisco VA Medical Center (US)
- Mayo Clinic (US)
- University of Wisconsin–Madison (US)
- Fordham University (US)
- University of California, San Francisco (US)
- University of California, Irvine (US)
- University of California System (US)
- Irvine University (US)
- Advanced Imaging Research (United States) (US)
- VA Long Beach Healthcare System (US)
- Northern California Institute for Research and Education (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/alz.14234
- Citations
- 14
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 7.60
Funders
- National Institute on Aging