Metal‐Free Aminophosphonation: Eco‐Friendly Synthesis and Photophysical Properties of Fluorescent 3‐(Aminoimidazo[1,2‐<i>a</i>]Pyridin‐2‐yl)Phosphonates
We report a novel, metal-free procedure for the direct aminophosphonation of imidazo[1,2-a]pyridines in green solvents under open air conditions. This method is characterized by its mild and sustainable conditions, ease of operation, scalability, and excellent functional group compatibility. The synthesized compounds exhibit promising photophysical properties, including significant Stokes shifts and quantum yields, making them potential candidates for innovative fluorescent probes.
Authors
- Silvia Roscales (ORCID: https://orcid.org/0000-0002-0738-3548)
- Aurelio G. Csákÿ (ORCID: https://orcid.org/0000-0002-2888-2231)
Institutions
- Universidad Complutense de Madrid (ES)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/anie.202412300
- Citations
- 5
- Primary Topic
- Synthesis and Reactivity of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 1.25
Funders
- Ministerio de Ciencia e Innovación