Investigating Neuroplasticity Changes Reflected by BDNF Levels in Astrocyte-Derived Extracellular Vesicles in Patients with Depression
This study provides human in vivo evidence supporting the neuroplasticity hypothesis of depression by demonstrating altered BDNF levels in ADEVs. ADEVs may be more suitable for developing biomarkers of depression than plasma-derived biomarkers.
Authors
- Xin‐hui Xie (ORCID: https://orcid.org/0000-0002-3603-3854)
- Shu‐xian Xu
- Zhongchun Liu (ORCID: https://orcid.org/0000-0002-3973-463X)
- Yan Tang
- Kun Li (ORCID: https://orcid.org/0009-0005-1519-6303)
- Lihong Zhang (ORCID: https://orcid.org/0000-0002-0418-8106)
- Kun Wang (ORCID: https://orcid.org/0009-0006-7995-3796)
Institutions
- Wuhan University (CN)
- Anhui Business College (CN)
- Renmin Hospital of Wuhan University (CN)
- West Anhui University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ijn.s477482
- Citations
- 17
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 3.97
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China