Correspondence to editorial on “Carvedilol to prevent hepatic decompensation of cirrhosis in patients with clinically significant portal hypertension stratified by new non-invasive model (CHESS2306)”

regarding the role of carvedilol in preventing hepatic decompensation of cirrhosis in patients with clinically significant portal hypertension (CSPH) stratified by a new non-invasive model. 2 Identifying predictors of decompensation in compensated patients is crucial, as the onset of decompensation is closely linked to mortality in cirrhosis. 3The hepatic venous pressure gradient (HVPG) is the gold stan-dard for assessing portal pressure and the foremost predictor of decompensation in cirrhotic patients. 4,5As noted in the editorial, however, the invasive procedure and restricted accessibility of HVPG measurements impede its widespread use.Due to this reason, non-invasive tests are extensively employed to detect CSPH in patients with compensated cirrhosis.The Baveno VII criteria provide specific thresholds for ruling in CSPH if liver stiffness measurement (LSM) 25 kPa or out if LSM15 kPa plus platelet count (PLT) 15010 9 /L, yet a grey zone exists for patients whose test results fall between these thresholds. 6In such cases, the ANTICI-

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Publication Details

Journal
Clinical and Molecular Hepatology
Published
2024-09-02
DOI
https://doi.org/10.3350/cmh.2024.0723
Primary Topic
Liver Disease and Transplantation
Type
article
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article

Correspondence to editorial on “Carvedilol to prevent hepatic decompensation of cirrhosis in patients with clinically significant portal hypertension stratified by new non-invasive model (CHESS2306)”

Xiaolong Qi, Chuan Liu, Gao‐Jun Teng, Ling Yang et al.
Clinical and Molecular Hepatology
Liver Disease and Transplantation
article

Correspondence to editorial on “Carvedilol to prevent hepatic decompensation of cirrhosis in patients with clinically significant portal hypertension stratified by new non-invasive model (CHESS2306)”

Xiaolong Qi, Chuan Liu, Gao‐Jun Teng, Ling Yang, Hong You
article en

Abstract

regarding the role of carvedilol in preventing hepatic decompensation of cirrhosis in patients with clinically significant portal hypertension (CSPH) stratified by a new non-invasive model. 2 Identifying predictors of decompensation in compensated patients is crucial, as the onset of decompensation is closely linked to mortality in cirrhosis. 3The hepatic venous pressure gradient (HVPG) is the gold stan-dard for assessing portal pressure and the foremost predictor of decompensation in cirrhotic patients. 4,5As noted in the editorial, however, the invasive procedure and restricted accessibility of HVPG measurements impede its widespread use.Due to this reason, non-invasive tests are extensively employed to detect CSPH in patients with compensated cirrhosis.The Baveno VII criteria provide specific thresholds for ruling in CSPH if liver stiffness measurement (LSM) 25 kPa or out if LSM15 kPa plus platelet count (PLT) 15010 9 /L, yet a grey zone exists for patients whose test results fall between these thresholds. 6In such cases, the ANTICI-

Clinical and Molecular HepatologyVol. 31(2)
Capital Medical University (CN), National Clinical Research Center for Digestive Diseases (CN), Zhongda Hospital Southeast University (CN), Beijing Friendship Hospital (CN), State Key Laboratory of Digital Medical Engineering (CN), Southeast University (CN)
Zero hunger
Openalex Percentile: Top 76%
Liver Disease and Transplantation
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