Craniospinal irradiation and/or intraventricular radioimmunotherapy after high‐dose chemotherapy and autologous stem cell rescue in patients with CNS retinoblastoma—Safety and outcomes
CSI (23.4 Gy) alone or in conjunction with intraventricular RIT may have clinical utility in eliminating persistent MRD post HDC-ASCT, contributing to improved disease-free survival in patients with CNS RB. This treatment strategy merits evaluation in a prospective, multicenter clinical trial for patients with CNS metastatic RB.
Authors
- Jasmine H. Francis (ORCID: https://orcid.org/0000-0002-7637-3108)
- Jonathan D. Fish (ORCID: https://orcid.org/0000-0003-4498-1843)
- Matthias A. Karajannis (ORCID: https://orcid.org/0000-0002-7151-6528)
- Neeta D. Pandit-Taskar (ORCID: https://orcid.org/0000-0003-1551-2036)
- Mauricio Rendon Bernot
- Kim Kramer (ORCID: https://orcid.org/0000-0002-3803-878X)
- Yasmin Khakoo (ORCID: https://orcid.org/0000-0003-1633-6759)
- Elizabeth Klein (ORCID: https://orcid.org/0000-0002-9735-4862)
- Carolyn Fein Levy (ORCID: https://orcid.org/0000-0002-9285-2248)
- Sameer Farouk Sait (ORCID: https://orcid.org/0000-0001-6715-2402)
- David H. Abramson (ORCID: https://orcid.org/0000-0002-0118-6391)
- Barbara Spitzer (ORCID: https://orcid.org/0000-0003-1603-1381)
- Ira J. Dunkel (ORCID: https://orcid.org/0000-0001-8091-6067)
- Sofia Haque (ORCID: https://orcid.org/0000-0003-4673-9997)
- Suzanne L. Wolden (ORCID: https://orcid.org/0000-0002-5234-4134)
- Stephen A. Sands (ORCID: https://orcid.org/0000-0003-4550-263X)
- Nancy A. Kernan (ORCID: https://orcid.org/0000-0003-1417-1823)
- Onur Yıldırım (ORCID: https://orcid.org/0000-0002-1586-1933)
- Maria Donzelli
Institutions
- Hackensack University Medical Center (US)
- Memorial Sloan Kettering Cancer Center (US)
- Hofstra University (US)
- Cornell University (US)
- Cohen Children's Medical Center (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1002/pbc.31297
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Memorial Sloan-Kettering Cancer Center
- National Cancer Institute