Effects of beta-blockers on quality of life and well-being in patients with myocardial infarction and preserved left ventricular function—a prespecified substudy from REDUCE-AMI
Among patients after AMI with preserved left ventricular ejection fraction, self-reported quality of life and well-being was not significantly different in individuals randomized to routine long-term beta-blocker therapy as compared to individuals with no beta-blocker use. These results appear consistent regardless of adherence to randomized treatment and across subgroups which emphasizes the need for a careful individual risk-benefit evaluation prior to initiation of beta-blocker treatment.
Authors
- Katarina Mars (ORCID: https://orcid.org/0000-0002-6739-1558)
- Sophia Humphries (ORCID: https://orcid.org/0000-0002-3680-6351)
- Jörg Lauermann (ORCID: https://orcid.org/0000-0003-0982-0489)
- Joakim Alfredsson (ORCID: https://orcid.org/0000-0002-1415-7178)
- Erik Olsson (ORCID: https://orcid.org/0000-0002-1591-7407)
- Tomas Jernberg (ORCID: https://orcid.org/0000-0003-1695-379X)
- Annica Ravn‐Fischer (ORCID: https://orcid.org/0000-0003-2585-1592)
- Patric Karlström (ORCID: https://orcid.org/0000-0002-2441-0245)
- Robin Hofmann (ORCID: https://orcid.org/0000-0002-8907-895X)
- Martin N. Jonsson (ORCID: https://orcid.org/0000-0002-3539-8317)
- Bertil Lindahl (ORCID: https://orcid.org/0000-0002-5795-0061)
- Philip Leissner (ORCID: https://orcid.org/0000-0003-0787-9102)
- Troels Yndigegn (ORCID: https://orcid.org/0000-0002-8960-2125)
- David Erlinge (ORCID: https://orcid.org/0000-0003-3042-5766)
- Claes Held (ORCID: https://orcid.org/0000-0001-9402-7404)
- Thomas Kellerth (ORCID: https://orcid.org/0000-0002-7397-3124)
Institutions
- Linköping University (SE)
- Uppsala University (SE)
- Lund University (SE)
- Sahlgrenska University Hospital (SE)
- Danderyds sjukhus (SE)
- Karolinska Institutet (SE)
- Stockholm South General Hospital (SE)
- Glanrhyd Hospital (GB)
- Karlstad Central Hospital (SE)
- Skåne University Hospital (SE)
- Ryhov Hospital Jönköping (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- European Heart Journal - Cardiovascular Pharmacotherapy
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1093/ehjcvp/pvae062
- Citations
- 9
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 3.62
Funders
- Riksförbundet HjärtLung
- Vetenskapsrådet