Effect of tumor-derived extracellular vesicle-shuttled lncRNA MALAT1 on proliferation, invasion and metastasis of triple-negative breast cancer by regulating macrophage M2 polarization via the POSTN/Hippo/YAP axis
TNBC-EV-derived MALAT1 activated the Hippo/YAP axis by up-regulating POSTN, thereby inducing M2 polarization to promote TNBC occurrence and metastasis in vivo.
Authors
- Ziyun Zhang
- Xuedong Wang (ORCID: https://orcid.org/0000-0003-3430-1082)
- Juan Gu (ORCID: https://orcid.org/0000-0001-8723-1044)
- Xinping Wang (ORCID: https://orcid.org/0009-0007-6090-2830)
- Yueping Wang (ORCID: https://orcid.org/0000-0002-9815-9954)
- Q Jian
Institutions
- Anhui University (CN)
- Anhui University of Science and Technology (CN)
- Anhui Provincial Hospital (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.tranon.2024.102076
- Citations
- 12
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.81