Histogenesis of suprarenal gland, kidney and liver in mice Mus musculus

Objective: The postnatal development of the suprarenal glands, liver, kidney in mice was examined in this work using histological and histochemical techniques. For this reason, it is acceptable to use mice in scientific study. Materials and methods: Thirty two samples of mices suprarenal gland, liver, and kidney; eight at each age were used in the experiment (one day, seven day, fourteen day, twenty one day). Results: The adrenal glands were enclosed in a well-developed capsule, the cortex was divided in the glomerulosa, fasciculate, and reticularis areas, and the medulla consisted of large, pale-stained hexagonal cells arrangements in tiny anastomosing strings had together by a reticular fiber and divided through sinusoids in all ages with varying thickness of the layers. When the first day of life; liver was enclosed in a thin capsule; after 14 to 21 days, it was enclosed in a thick capsule. The parenchyma consisted of hepatocytes, which were surrounded by a central vein. The sinusoids further divided the parenchyma, with Kupffer cells protruding next to the endothelial cells that bordered the hepatic sinusoids. Depending on the age, the liver measurements changed. There was a modest amount of collagen fiber covering the kidney. Renal corpuscles are classified as cortex, midcortical, or juxtamedullary; as they age, their diameter increases. Proximal convoluted tubules are the longest; they have a brush border and are surrounded by cuboidal epithelial tissue; distal convoluted tubules are shorter. Additionally, henle loops were long at some ages but short at one-day and adult ages. The corpuscle and nephron lumens were bigger in adults. In contrast, there were less collagen fibers in the thick renal capsule and gap in other age groups.