ATM Activation is Key in Vasculogenic Mimicry Formation by Glioma Stem-like Cells.
VM may predict a poor GBM prognosis and is associated with pATM expression. We propose that pATM promotes VM through extracellular matrix modulation and VE-Cadherin / pVEGFR-2 activation, thereby highlighting ATM activation as a potential target for enhancing anti-angiogenesis therapies for GBM.
Authors
- Haibo Wu (ORCID: https://orcid.org/0000-0003-0817-9191)
- Wei Wang (ORCID: https://orcid.org/0000-0002-0355-4848)
- Yuan Li (ORCID: https://orcid.org/0000-0001-6474-746X)
- Xue Kong (ORCID: https://orcid.org/0009-0008-9017-4405)
- Jia Xin Tang
- Jing Xie (ORCID: https://orcid.org/0000-0001-6113-1336)
Institutions
- University of Science and Technology of China (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3967/bes2024.127
- Citations
- 2
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.47