Ertugliflozin to Reduce Arrhythmic Burden in Patients with ICDs/CRT-Ds
Ertugliflozin reduced sustained ventricular tachycardia or ventricular fibrillation events in adults with heart failure and an ICD compared with placebo; however, our trial ended early and thus results should be interpreted with caution. (Funded by Investigator-initiated Studies Program of Merck Sharp & Dohme Corp and Pfizer; EudraCT number, 2020-002581-14; ClinicalTrials.gov number NCT04600921.).
Authors
- Ewald Kolesnik (ORCID: https://orcid.org/0000-0002-9349-8068)
- Martin Manninger (ORCID: https://orcid.org/0000-0002-0545-4373)
- Dirk von Lewinski (ORCID: https://orcid.org/0000-0001-9996-6128)
- Franz Xaver Roithinger
- Martin Benedikt (ORCID: https://orcid.org/0000-0003-0480-2521)
- Faisal Aziz (ORCID: https://orcid.org/0000-0002-0109-2969)
- Andreas Zirlik (ORCID: https://orcid.org/0000-0001-6290-3297)
- Abderrahim Oulhaj (ORCID: https://orcid.org/0000-0002-5330-904X)
- Douglas S. Scherr (ORCID: https://orcid.org/0000-0001-5868-5493)
- Clemens Steinwender (ORCID: https://orcid.org/0000-0002-4963-5563)
- Harald Sourij (ORCID: https://orcid.org/0000-0003-3510-9594)
- Michael Nürnberg (ORCID: https://orcid.org/0009-0003-7615-5236)
- Markus Wallner (ORCID: https://orcid.org/0000-0001-7692-892X)
- Norbert J. Tripolt (ORCID: https://orcid.org/0000-0002-7566-2047)
- Marianne Gwechenberger (ORCID: https://orcid.org/0000-0002-3066-8947)
- Peter N. Pferschy
- Martin Martinek (ORCID: https://orcid.org/0000-0002-8895-8488)
- Ursula Rohrer (ORCID: https://orcid.org/0000-0002-5278-6362)
- Johannes Widkal
- Simon Leiter
- Markus Stühlinger
Institutions
- Innsbruck Medical University (AT)
- Khalifa University of Science and Technology (AE)
- Universität Innsbruck (AT)
- Medical University of Graz (AT)
- Fachhochschule Wiener Neustadt (AT)
- Kepler Universitätsklinikum (AT)
- Krankenhaus der Elisabethinen (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- NEJM Evidence
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1056/evidoa2400147
- Citations
- 15
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 5.37