Efflux of TolC protein to different antimicrobials can be replaced by other outer membrane proteins with similar β-barrel structures in extraintestinal pathogenic <i>Escherichia coli</i>
All five OMPs can replace the TolC protein to play the efflux role in pumping out the drugs from the periplasm to the extracellular space with the help of proteins AcrA and AcrB.
Authors
- Chenglong Yang (ORCID: https://orcid.org/0009-0009-3529-1788)
- Ailian Cui
- Shaowen Li (ORCID: https://orcid.org/0000-0002-5267-9639)
- Xue Bao
- Qi Huang (ORCID: https://orcid.org/0000-0002-1600-1169)
- Tian Li
- Xianrong Meng
- Yanlin Wang (ORCID: https://orcid.org/0000-0001-7423-6815)
Institutions
- Huazhong Agricultural University (CN)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1093/jambio/lxae214
- Citations
- 3
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.51
Funders
- National Key Research and Development Program of China