Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes

BAT is a promising tool for delabelling and endotyping CHT-HSRs, especially Type I reactions to PSs, possibly identifying patients at risk of positive DPT. ST seems useful in confirming CHT-HSRs, especially PS-induced reactions, and DPT remains the gold standard, being essential even in moderate-risk patients.

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Institutions

Publication Details

Journal
Allergy
Published
2024-08-31
DOI
https://doi.org/10.1111/all.16296
Citations
8
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
3.58

Funders

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article

Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes

Clara Lebrón‐Martín, Silvia Calvo‐Serrano, Paula Vázquez‐Revuelta, Marina Labella et al.
8 citations
Allergy
Drug-Induced Adverse Reactions
3.58
article

Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes

Clara Lebrón‐Martín, Silvia Calvo‐Serrano, Paula Vázquez‐Revuelta, Marina Labella, Cristobalina Mayorga, Rubén Fernández‐Santamaría, Gádor Bogas, Inmaculada Doña, Ricardo Madrigal‐Burgaleta, E. Villar-Chamorro, Adriana Ariza, Marı́a José Torres, Susana Martín‐Clavo
article en
8 citations

Abstract

BAT is a promising tool for delabelling and endotyping CHT-HSRs, especially Type I reactions to PSs, possibly identifying patients at risk of positive DPT. ST seems useful in confirming CHT-HSRs, especially PS-induced reactions, and DPT remains the gold standard, being essential even in moderate-risk patients.

AllergyVol. 80(1)
St Bartholomew's Hospital (GB), Institut Català d'Ornitologia (ES), Barts Health NHS Trust (GB), Bellvitge University Hospital (ES), Institut Català d'Oncologia (ES), Hospital Regional Universitario de Málaga (ES), Hospital Materno-Infantil (ES), Hospital Clínico Universitario Virgen de la Victoria (ES), Instituto de Investigación Biomédica de Málaga (ES), Universidad de Málaga (ES)
Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, European Regional Development Fund
Good health and well-being
Openalex Percentile: Top 7%
Drug-Induced Adverse Reactions
3.58
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