A Case of Severe Copper Sulphate Poisoning

Copper sulphate poisoning is a serious medical concern, particularly in regions where its use is prevalent in various industries and where accidental or intentional ingestion poses risks, such as in Sri Lanka. We present the case of an 18-year-old female who ingested a substantial amount of copper sulphate, leading to severe toxicity and multiple complications. Despite initial management with gastric lavage and activated charcoal, the patient developed intravascular hemolysis, methemoglobinemia, rhabdomyolysis, acute liver injury, and aspiration pneumonia. Treatment involved supportive measures, including fluid resuscitation, blood transfusions, and antibiotics, along with chelation therapy using penicillamine. Notably, our patient exhibited favorable clinical progress and recovery within a week of admission. This case underscores the importance of prompt recognition and management of copper sulphate poisoning, emphasizing the potential for severe complications and the need for further research to establish standardized treatment protocols. Restricting access to copper sulfate in its powdered form may serve as a preventive measure against intentional ingestion, thereby reducing the incidence of poisoning cases.

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Publication Details

Journal
Canadian Journal of Medicine
Published
2024-08-31
DOI
https://doi.org/10.33844/cjm.2024.6040
Primary Topic
Poisoning and overdose treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case of Severe Copper Sulphate Poisoning

Deepa Amarasekara, Sumaiya Lahir, Peumini Rajapakse, Pubudu Jayasekara
Canadian Journal of Medicine
Poisoning and overdose treatments
article

A Case of Severe Copper Sulphate Poisoning

Deepa Amarasekara, Sumaiya Lahir, Peumini Rajapakse, Pubudu Jayasekara
article en

Abstract

Copper sulphate poisoning is a serious medical concern, particularly in regions where its use is prevalent in various industries and where accidental or intentional ingestion poses risks, such as in Sri Lanka. We present the case of an 18-year-old female who ingested a substantial amount of copper sulphate, leading to severe toxicity and multiple complications. Despite initial management with gastric lavage and activated charcoal, the patient developed intravascular hemolysis, methemoglobinemia, rhabdomyolysis, acute liver injury, and aspiration pneumonia. Treatment involved supportive measures, including fluid resuscitation, blood transfusions, and antibiotics, along with chelation therapy using penicillamine. Notably, our patient exhibited favorable clinical progress and recovery within a week of admission. This case underscores the importance of prompt recognition and management of copper sulphate poisoning, emphasizing the potential for severe complications and the need for further research to establish standardized treatment protocols. Restricting access to copper sulfate in its powdered form may serve as a preventive measure against intentional ingestion, thereby reducing the incidence of poisoning cases.

Canadian Journal of MedicineVol. 0(0)
Colombo North Teaching Hospital (LK)
Openalex Percentile: Top 75%
Poisoning and overdose treatments
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