A proactive grey wolf optimization for improving bioinformatic systems with high dimensional data

Abstract This paper introduces a new methodology for optimization problems, combining the Grey Wolf Optimizer (GWO) with Simi-stochastic search processes. Intelligent optimizations represent an advanced approach in machine learning and computer applications, aiming to reduce the number of features used in the classification process. Optimizing bioinformatics datasets is crucial for information systems that classify data for intelligent tasks. The proposed A-Proactive Grey Wolf Optimization (A-GWO) solves stagnation in GWO by applying a dual search with a Simi-stochastic search. This target is achieved by distributing the population into two groups using a different search technique. The model's performance is evaluated using two benchmarks: the Evolutionary Computation Benchmark (CEC 2005) and seven popular biological datasets. A-GWO demonstrates highly improved efficiency in comparision to the original GWO and Particle Swarm Optimization (PSO). Specifically, it enhances exploration in 66% of CEC functions and achieves high accuracy in 70% of biological datasets.