Retargeting of heterologous enzymes results in improved β-carotene synthesis in <i>Saccharomyces cerevisiae</i>
The retargeting of heterologously expressed pathway enzymes improves β-carotene production in S. cerevisiae, implicating extensive inter-organellar transport phenomena of carotenoid precursors. In addition, strong overexpression of carotenoid biosynthetic enzymes and the optimization of cultivation conditions are required for high contents.
Authors
- Gabriela Gogg‐Fassolter
- Simon Arhar
- Karin Athenstaedt (ORCID: https://orcid.org/0000-0001-7198-3989)
- Rupert Pfaller
- Thomas Züllig (ORCID: https://orcid.org/0000-0002-8483-0962)
- Klaus Natter (ORCID: https://orcid.org/0000-0002-4483-9321)
- Thomas Lins
Institutions
- University of Graz (AT)
- Wacker Group (Germany) (DE)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1093/jambio/lxae224
- Citations
- 6
- Primary Topic
- Plant biochemistry and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.40