Generating Dorsal Root Ganglion Explant and Dissociated Cell Culture

Source: Fornaro, M. et al., Adult Mouse DRG Explant and Dissociated Cell Models to Investigate Neuroplasticity and Responses to Environmental Insults Including Viral Infection. J. Vis. Exp. (2018). This video demonstrates a method to develop dorsal root ganglia or DRG explant culture and DRG-dissociated cell models using isolated mouse DRG tissues. These models help to study various mechanisms with neuron-glial interactions in a controlled environment.