Sleep fragmentation despite intact rest-activity patterns in premanifest Huntington's disease: An actigraphy study
Despite intact rest-activity patterns and similar subjective sleep quality to HC, greater sleep fragmentation is a prominent and early feature in Pre-HD. Therefore, reducing sleep fragmentation may be a potential target for sleep intervention in HD. Longitudinal studies using larger samples are needed to assess sleep across the disease spectrum and its impact on clinical outcomes, like cognition.
Authors
- Yifat Glikmann‐Johnston (ORCID: https://orcid.org/0000-0002-6128-7768)
- Melinda L. Jackson (ORCID: https://orcid.org/0000-0003-4976-8101)
- Jessica E. Manousakis (ORCID: https://orcid.org/0000-0002-2353-377X)
- Julie C. Stout (ORCID: https://orcid.org/0000-0001-9637-8590)
- Clare Anderson (ORCID: https://orcid.org/0000-0002-5086-4865)
- Emily S. Fitzgerald (ORCID: https://orcid.org/0000-0002-4353-5852)
- Meg Rankin
Institutions
- Monash University (AU)
Publication Details
- Journal
- Sleep Medicine
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1016/j.sleep.2024.08.026
- Citations
- 3
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Huntington's Disease Society of America
- Department of Education and Training