Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system
The results show the presence of all analyzed receptors in the efferent LDS. With an average tear passage time of 3 min and a relatively large mucosal surface area, the LDS could therefore be considered as a portal of entry and conduit for SARS-CoV-2. In addition, it represents a surface that should be taken into consideration in the administration of topically applied medication to the ocular surface.
Authors
- Martin Schicht (ORCID: https://orcid.org/0000-0001-5155-5477)
- Ingrid Zahn (ORCID: https://orcid.org/0000-0002-6477-4940)
- Minas T. Coroneo (ORCID: https://orcid.org/0000-0002-3061-2011)
- Friedrich Paulsen (ORCID: https://orcid.org/0000-0002-0527-0953)
- Mohammad Javed Ali (ORCID: https://orcid.org/0000-0002-6363-9202)
- Anna-Lena Rau
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- L V Prasad Eye Institute (IN)
- Prince of Wales Hospital (AU)
Publication Details
- Journal
- The Ocular Surface
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1016/j.jtos.2024.08.016
- Citations
- 3
- Primary Topic
- Retinal and Optic Conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.62