USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα
Our study revealed the possibility that inhibiting USP36 combined with tamoxifen could provide a potential therapy for breast cancer.
Authors
- Jiaoyan Li (ORCID: https://orcid.org/0000-0002-9751-6809)
- Chenmiao Zhang
- Dongyi Liu (ORCID: https://orcid.org/0000-0002-7990-5018)
- Zhongbo Li (ORCID: https://orcid.org/0000-0002-1895-7201)
- Mingxi Fu
- Huijie Yang (ORCID: https://orcid.org/0000-0002-6103-3979)
- Jian Zhu (ORCID: https://orcid.org/0000-0003-0171-4251)
- Jiayao Cui (ORCID: https://orcid.org/0000-0003-4516-5549)
- Peng Su (ORCID: https://orcid.org/0000-0002-7000-0474)
- Penghe Yang
- Xin Li (ORCID: https://orcid.org/0000-0001-6432-3966)
- Shuqing Zhang (ORCID: https://orcid.org/0000-0003-1648-6423)
- Fangyu Shen (ORCID: https://orcid.org/0000-0001-9025-8678)
- Zhao Zhang (ORCID: https://orcid.org/0000-0002-5697-8011)
- Ting Ting Zhuang
- Lei Yuan
Institutions
- Shandong University (CN)
- Second Hospital of Shandong University (CN)
- Zhengzhou People's Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
- Qilu Hospital of Shandong University (CN)
- Henan Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1186/s13046-024-03160-2
- Citations
- 12
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Foundation of Henan Educational Committee
- University of Science and Technology Liaoning
- Natural Science Foundation of Henan Province
- Natural Science Foundation of Shandong Province
- Taishan Scholar Foundation of Shandong Province
- Xinxiang Medical University
- Henan Province Science and Technology Innovation Talent Program
- Science and Technology Innovation Talents in Universities of Henan Province