<scp>DNA</scp> damage induced <scp>PARP</scp>‐1 overactivation confers paclitaxel‐induced neuropathic pain by regulating mitochondrial oxidative metabolism
The findings provide a novel insight into the mechanism of DNA oxidative damage in the development of PINP and implicate PARP-1 as a possible therapeutic target for clinical PINP treatment.
Authors
- Ya‐Qun Zhou (ORCID: https://orcid.org/0000-0001-6917-4808)
- Qiu Qiu
- Y ZHOU
- M. Ge
- Junjie Hu (ORCID: https://orcid.org/0000-0003-2522-4724)
- Hui Yang (ORCID: https://orcid.org/0000-0001-6498-5126)
- Zhiheng Liu (ORCID: https://orcid.org/0000-0001-6711-4801)
- Dawei Ye (ORCID: https://orcid.org/0000-0002-5114-1378)
- Yu‐ke Tian
Institutions
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Queen Mary Hospital (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Shenzhen University Health Science Center (CN)
- Tongji Hospital (CN)
- Shenzhen Second People's Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1111/cns.70012
- Citations
- 8
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.26
Funders
- National Natural Science Foundation of China