Unraveling the potential effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on the Protein structure and function of the human SLC30A8 gene on type 2 diabetes and colorectal cancer: An In silico approach
Finally, the study found eight highly deleterious missense nsSNPs in the <i>SLC30A8</i> gene that can be helpful for further proteomic and genomic studies for T2D and colorectal cancer diagnosis. These findings also pave the way for personalized treatments using biomarkers and more effective healthcare strategies.
Authors
- Kawsar Ahmed (ORCID: https://orcid.org/0000-0002-4034-9819)
- Md Habibur Rahman (ORCID: https://orcid.org/0000-0002-5068-2690)
- Md. Shahinur Rahman (ORCID: https://orcid.org/0000-0001-9430-2381)
- Md. Tanvir Hossaın (ORCID: https://orcid.org/0000-0001-8572-2560)
- Asif Ahsan (ORCID: https://orcid.org/0000-0001-6184-0554)
- Francis M. Bui (ORCID: https://orcid.org/0000-0002-8799-5965)
- Md. Arif Hossen
- Md. Arju Hossain (ORCID: https://orcid.org/0000-0002-8588-943X)
- M. M. Uddin
- Kamrul Hasan Shamim
Institutions
- Umm al-Qura University (SA)
- Daffodil International University (BD)
- Bangladesh Agricultural University (BD)
- University of Saskatchewan (CA)
- Islamic University (BD)
- Mawlana Bhashani Science and Technology University (BD)
- Université Bourgogne Franche-Comté (FR)
- Primeasia University (BD)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37280
- Citations
- 9
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.10