Genetic causal association between lipidomic profiles, inflammatory proteomics, and aortic stenosis: a Mendelian randomization investigation
This study reveals complex lipid and protein interactions in AS, identifying potential molecular targets for therapy. These results go beyond traditional lipid profiling and significantly advance our genetic and molecular understanding of AS, highlighting potential pathways for intervention and prevention.
Authors
- Guofeng Shao (ORCID: https://orcid.org/0000-0001-5609-7196)
- Ni Li (ORCID: https://orcid.org/0000-0001-5530-7745)
- Linwen Zhu (ORCID: https://orcid.org/0000-0002-6210-9816)
- Huoshun Shi
- Lebo Sun (ORCID: https://orcid.org/0000-0002-3229-4790)
Institutions
- Ningbo University (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1186/s40001-024-02014-z
- Citations
- 3
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.21
Funders
- Wu Jieping Medical Foundation