Macrophage MKL1 contributes to cardiac fibrosis in a mouse model of myocardial infarction
Our data demonstrate that MKL1 in macrophages contributes to cardiac fibrosis pathogenesis and reinforce the notion that targeting MKL1 may yield effective antifibrotic therapeutics in the heart.
Authors
- Yameng Kuai
- Baoyu Chen (ORCID: https://orcid.org/0000-0002-6366-159X)
- Yuwen Zhu (ORCID: https://orcid.org/0000-0003-1434-6590)
- Qianwen Zhao (ORCID: https://orcid.org/0009-0003-0361-1181)
- Wenkui Yu
- Ke Cao (ORCID: https://orcid.org/0000-0001-6508-5285)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Life Sciences
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1016/j.lfs.2024.123036
- Citations
- 4
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China