Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction
These results highlight the potential of macrophage-derived EVs as a powerful endogenous candidate for iron chelation therapy, offering a novel and promising therapeutic approach to protect against iron overload-induced injury in MI and other cardiovascular diseases.
Authors
- Zhelong Li (ORCID: https://orcid.org/0000-0001-5947-8306)
- Rui Yu
- Dong Guo (ORCID: https://orcid.org/0000-0001-7057-2838)
- Tingwei Peng
- Mingchuan Liu
- Feng Fu (ORCID: https://orcid.org/0000-0003-3752-4628)
- Xue Yang (ORCID: https://orcid.org/0000-0002-3919-8013)
- Jing Geng (ORCID: https://orcid.org/0000-0003-1775-3490)
- Lang Hu (ORCID: https://orcid.org/0000-0001-7627-652X)
- Ying Wang (ORCID: https://orcid.org/0000-0002-7852-386X)
- Yan Li (ORCID: https://orcid.org/0000-0003-0096-0813)
- Xiaoliang Zhang (ORCID: https://orcid.org/0000-0002-0433-4636)
- Qi Liang (ORCID: https://orcid.org/0000-0002-0201-9333)
- Siying Pu
Institutions
- Air Force Engineering University (CN)
- Tang Du Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1186/s12951-024-02800-1
- Citations
- 12
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Natural Science Foundation of China