Ischemic stroke associated with amyloid‐related imaging abnormalities in a patient treated with lecanemab
We report a patient who developed severe amyloid-related imaging abnormalities (ARIA) after treatment with lecanemab. Our report suggests that ischemic strokes may be a novel imaging feature of ARIA. Our report highlights the need for high clinical suspicion for seizures in ARIA.
Authors
- Ilya M. Nasrallah (ORCID: https://orcid.org/0000-0003-2346-7562)
- Sashank Prasad (ORCID: https://orcid.org/0000-0003-2465-4810)
- Yombe Fonkeu (ORCID: https://orcid.org/0000-0002-8226-1129)
- David A. Wolk (ORCID: https://orcid.org/0000-0002-3554-3481)
- Michela Rosso (ORCID: https://orcid.org/0000-0002-3359-9094)
- Alec W. Gibson (ORCID: https://orcid.org/0000-0002-5709-4146)
- Michael H. Guo (ORCID: https://orcid.org/0000-0002-1357-6389)
- Eli J. Cornblath (ORCID: https://orcid.org/0000-0002-2619-8778)
- Aaron Rothstein (ORCID: https://orcid.org/0000-0002-8480-8220)
- Holly Elser (ORCID: https://orcid.org/0000-0003-1781-904X)
Institutions
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1002/alz.14223
- Citations
- 12
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.92
Funders
- University of Pennsylvania
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke