Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women
A single combined measure of high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) levels among initially healthy U.S. women was predictive of incident cardiovascular events during a 30-year period. These data support efforts to extend strategies for the primary prevention of atherosclerotic events beyond traditional 10-year estimates of risk. (Funded by the National Institutes of Health; Women's Health Study ClinicalTrials.gov number, NCT00000479.).
Authors
- Nader Rifai (ORCID: https://orcid.org/0000-0003-0706-2477)
- I‐Min Lee (ORCID: https://orcid.org/0000-0002-1083-6907)
- M. Vinayaga Moorthy (ORCID: https://orcid.org/0000-0002-0983-3215)
- Nancy R. Cook (ORCID: https://orcid.org/0000-0002-9705-0842)
- Julie E. Buring (ORCID: https://orcid.org/0000-0003-2648-8692)
- Paul M. Ridker (ORCID: https://orcid.org/0000-0003-1249-4522)
Institutions
- Brigham and Women's Hospital (US)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1056/nejmoa2405182
- Citations
- 201
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 114.55
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- National Cancer Institute