Giant Dermatofibrosarcoma Protuberans Originating from a Keloid Scar-A Case Report and Review

Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous sarcoma derived from dermal fibroblasts and accounts for 1-6% of all cutaneous soft tissue sarcomas.These low-grade tumors typically follow an indolent early course marked by slow growth but have a small potential to exhibit rapid growth with high-grade transformation.DFSPs are clinically similar to benign fibro proliferative skin tumors such as keloids, which may lead to misdiagnosis and delays in treatment.We present a case of DFSP originating from a keloid scar on the right breast.Here, we highlight the difficulty of timely diagnosis and need for multidisciplinary care.Excision of large tumors often leave significant defects requiring local tissue rearrangements, skin grafts, or complex reconstruction.Further, we review pertinent literature and outline the nuanced challenges of DFSP management.