Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation
Among patients with heart failure with moderate to severe functional mitral regurgitation who received medical therapy, the addition of transcatheter mitral-valve repair led to a lower rate of first or recurrent hospitalization for heart failure or cardiovascular death and a lower rate of first or recurrent hospitalization for heart failure at 24 months and better health status at 12 months than medical therapy alone. (Funded by Abbott Laboratories; RESHAPE-HF2 ClinicalTrials.gov number, NCT02444338.).
Authors
- Efstratios K. Theofilogiannakos
- Gerd Hasenfuß (ORCID: https://orcid.org/0000-0002-5942-361X)
- Malte Kelm (ORCID: https://orcid.org/0000-0003-0060-1052)
- Mark C. Petrie (ORCID: https://orcid.org/0000-0002-6333-9496)
- Finn Gustafsson (ORCID: https://orcid.org/0000-0003-2144-341X)
- Karl‐Heinz Kück (ORCID: https://orcid.org/0000-0003-2649-3870)
- Frank Thomas Ruschitzka (ORCID: https://orcid.org/0000-0001-5972-0596)
- Marius Placzek (ORCID: https://orcid.org/0000-0002-8663-5378)
- Michael Chrissoheris (ORCID: https://orcid.org/0000-0002-5399-1309)
- Antoni Bayés‐Genís (ORCID: https://orcid.org/0000-0002-3044-197X)
- Fausto José Pinto (ORCID: https://orcid.org/0000-0002-8034-4529)
- John G.F. Cleland (ORCID: https://orcid.org/0000-0002-1471-7016)
- Piotr Ponikowski (ORCID: https://orcid.org/0000-0002-3391-7064)
- Evelyn Santiago‐Vacas (ORCID: https://orcid.org/0000-0001-7511-406X)
- Javed Butler (ORCID: https://orcid.org/0000-0001-7683-4720)
- Gerasimos S Filippatos (ORCID: https://orcid.org/0000-0002-5640-0332)
- Wojciech Wojakowski (ORCID: https://orcid.org/0000-0002-3681-5207)
- Vlasis N. Ninios (ORCID: https://orcid.org/0000-0002-0390-7172)
- Martin Geyer (ORCID: https://orcid.org/0000-0002-9935-8293)
- Łukasz Wiewiórka
- Grzegorz Smołka (ORCID: https://orcid.org/0000-0003-2031-822X)
- Jutta Heinrich
- Ulf Landmesser (ORCID: https://orcid.org/0000-0002-0214-3203)
- Konstantinos Spargias
- Marco Metra (ORCID: https://orcid.org/0000-0001-6691-8568)
- Stefan D. Anker
- Ralph-Stephan von Bardeleben
- Tim Friede (ORCID: https://orcid.org/0000-0001-5347-7441)
- Mitja Lainščak (ORCID: https://orcid.org/0000-0002-5922-4098)
- Alec Vahanian (ORCID: https://orcid.org/0000-0001-9413-4891)
- Tienush Rassaf (ORCID: https://orcid.org/0000-0001-8001-0265)
- Andreas M. Zeiher (ORCID: https://orcid.org/0000-0003-1711-5819)
- Panagiota Kourkoveli
- William T. Abraham (ORCID: https://orcid.org/0000-0003-4805-1037)
- Angelo Auricchio (ORCID: https://orcid.org/0000-0003-2116-6993)
- Monika Diek
- Marianna Adamo (ORCID: https://orcid.org/0000-0002-3855-1815)
- Zbigniew F. Kalarus (ORCID: https://orcid.org/0000-0003-3921-7234)
- Ottavio Alfieri (ORCID: https://orcid.org/0000-0003-1065-8052)
- Krzysztof Reczuch (ORCID: https://orcid.org/0000-0002-1699-739X)
- Wilhelm Haverkamp (ORCID: https://orcid.org/0000-0002-6183-2519)
- Friedrich Koehler (ORCID: https://orcid.org/0000-0003-0441-4123)
- Aldo P. Maggioni (ORCID: https://orcid.org/0000-0003-2764-6779)
- T. Ruf (ORCID: https://orcid.org/0000-0003-4540-6621)
- Ilias Ninios (ORCID: https://orcid.org/0000-0002-4444-3781)
- Jose Luis Zamorano
- Roberto Ferrari (ORCID: https://orcid.org/0000-0003-2046-9175)
- Κωνσταντίνος Παπαδόπουλος (ORCID: https://orcid.org/0000-0001-7356-2379)
- Alper Öner (ORCID: https://orcid.org/0000-0001-6116-7021)
- Ulrich Schäfer (ORCID: https://orcid.org/0000-0002-9684-320X)
- M. Gross
- P. Christian Schulze
- Wolfgang Schillinger
- Joern Tongers
- Mahir Karakas
- M M Khan
- Nikolaos Mezilis
Institutions
- Deutsches Herzzentrum der Charité (DE)
- German Centre for Cardiovascular Research (DE)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1056/nejmoa2314328
- Citations
- 201
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 80.81