Assistant Professor of Cardiology and angiology, Cardiology Department, Faculty of Medicine, Alexandria University, Egypt

Background: Sickle-cell disease is a broad term that refers to a variety of diseases. The majority of those affected have chronic anemia, with a hemoglobin level of roughly 8 g/dl. The major issues emerge from red blood cells' tendency to become sickle-shaped and obstruct capillaries when oxygen tension is low, using patterns such as family-centered empowerment can be effectively promoting individual self-care behaviors. Family empowerment improves knowledge and attitudes, leading to improved performance and quality of care, improved self-care, accelerated patient recovery, and reduced complications of disease. Objective: This study aimed to assess the Family empowerment in the care of patients with sickle cell disease in Siwa Oasis. Settings: The study was conducted at the outpatient clinic provides a lot of services for patient with sickle cell disease such as (lab investigation , blood trance fusion and control pain crisis ) at Siwa General Hospital which is the only hospital at siwa oasis which serve about 30000 citizens Subjects: the data was collected from (112) caregivers in caring with patients suffering from Sickle cell disease treated in the previously mentioned setting. Tools: two tools were used,family structured interview including; Socio-demographic Characteristics questionnaire, and Health profile, and Family empowerment scale (FES) Results: More than half of the studied families had "high" level of family empowerment . More than quarter of the studied families had "moderate" level of family empowerment .and the minority of them had "low" level of family empowerment .There were statistical significant differences between level of empowerment and their age, gender, level of education, and place of residence. Conclusion: The present study concluded that the level of empowerment affected by the level of education, availability of resources, severity of the disease, and the onset of the disease also the level to which extent this families have been empowered . Recommendations: Creating an integrated system to support people with sickle cell anemia by providing specialists, treatments and necessary examinations .