An Atypical Presentation of Acute Generalized Exanthematous Pustulosis Induced by Use of Meropenem: A Case Report and Literature Review

Acute generalized exanthematous pustulosis (AGEP) is a rare dermatological disorder characterized by the development of sterile pustular lesions on erythematous and edematous skin, followed by desquamation of the affected regions. The majority of cases occur following the administration of antimicrobials and antihypertensives. Our case report illustrates the atypical presentation of AGEP in an elderly female following treatment with meropenem for an infected pressure ulcer. Only a limited number of meropenem-associated AGEP have been documented. Our patient's presentation also highlights the difficulty of diagnosing AGEP and its similarity to other rare, drug-associated rashes. By illustrating this atypical clinical presentation of AGEP and highlighting its association with meropenem, we hope to provide insight to clinicians dealing with similar presentations.