Depression exacerbates myocardial ischemia-reperfusion injury in mice via CNR2 gene and MIF-AMPK signaling pathway
The activation of CNR2 in myocardium following I/R is impeded by depression, thereby exacerbating myocardial I/R injury through attenuation of the MIF-AMPK signaling pathway activation.
Authors
- Jiafeng Lin (ORCID: https://orcid.org/0000-0003-1748-7794)
- Lu Qian (ORCID: https://orcid.org/0000-0001-6742-907X)
- Zhuoyuan Li (ORCID: https://orcid.org/0000-0001-6105-6540)
- Cong Lin (ORCID: https://orcid.org/0009-0002-1494-4427)
- Suqin Zhang (ORCID: https://orcid.org/0000-0002-4281-3435)
Institutions
- Wenzhou Medical University (CN)
Publication Details
- Journal
- International Journal of Cardiology
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1016/j.ijcard.2024.132505
- Citations
- 3
- Primary Topic
- Macrophage Migration Inhibitory Factor
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- Wenzhou Municipal Science and Technology Bureau
- Basic Research Project of Wenzhou City