Effect of Mucuna pruriens seed extract on depression-like behavior derived from mild traumatic brain injury in rats
<i>M. pruriens</i> extract did not decrease neurobehavioral impairment caused by mTBI. Nevertheless, it prevented depression-like behaviors starting three days after mTBI, reduced LP, and increased GSH in some brain areas. <i>Conclusions</i>: <i>M. pruriens</i> may prevent depression-like behaviors and reduce oxidative stress by decreasing LP and increasing concentrations of antioxidant compounds.
Authors
- Marina Martínez-Vargas (ORCID: https://orcid.org/0000-0002-3729-2161)
- Adán Pérez-Arredondo (ORCID: https://orcid.org/0000-0002-0479-6734)
- Camilo Rı́os (ORCID: https://orcid.org/0000-0002-3216-0119)
- Alfonso Mata-Bermúdez (ORCID: https://orcid.org/0000-0002-2234-7019)
- María de los Ángeles Martínez-Cárdenas
- Luz Navarro (ORCID: https://orcid.org/0000-0002-5519-0871)
- Araceli Dı́az-Ruiz (ORCID: https://orcid.org/0000-0002-1481-0966)
- Héctor Alonso Romero-Sánchez
- Agustino Martínez‐Antonio (ORCID: https://orcid.org/0000-0003-2231-5014)
- Ricardo Trejo-Chávez
Institutions
- Universidad Autónoma Metropolitana (MX)
- Instituto Nacional de Rehabilitación (MX)
- Instituto Nacional de Neurología y Neurocirugía (MX)
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Biomedicine
- Published
- 2024-08-30
- DOI
- https://doi.org/10.37796/2211-8039.1461
- Citations
- 6
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 2.21
Funders
- Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México