Гостре пошкодження нирок, асоційоване з кардіохірургічними втручаннями: ретроспективне дослідження

The aim – to analyze the factors of development of acute kidney injury (AKI) in the early postoperative period after coronary artery bypass grafting (CABG).Materials and methods. In this retrospective study, the medical records of 100 patients who underwent CABG with cardiopulmonary bypass (CPB) were analyzed. The main criterium for the diagnosis of AKI was a dynamics of creatinine level in the first 48 hours after surgery.Results. The frequency of AKI in our study was 26 %. Patients with AKI were characterized by significantly higher EuroSCORE II values (2.00±0.98 vs. 1.49±0.74, p=0.006), higher initial levels of urea (7.62±2.94 vs. 6.12±1,71, p=0.002) and creatinine (107.7±38.5 vs. 91.2±16.2, p=0.003), a higher frequency of initial albumin level below 40 g/l (9 (34.6 %) vs. 11 (14.9 %) of cases, p=0.030), a lower baseline hemoglobin level (137.8±13.2 g/l vs. 146.6±13.6 g/l, p=0.005) compared to patients without this complication. The total length of hospitalization of patients with AKI was significantly higher (14.3±5.45 days versus 12.6±3.05 days, p=0.048). Logistic regression showed that only oxygen delivery during CPB was associated with the development of AKI in the early postoperative period.Conclusion. The frequency of AKI in our study was 26 %. Optimizing the factors that influence the development of AKI may contribute to better postoperative results.