Natriuretic Peptides, Kidney Function, and Clinical Outcomes in Heart Failure With Preserved Ejection Fraction
The same NT-proBNP concentration predicts a substantially higher absolute risk of adverse outcomes for people with heart failure and reduced kidney function, compared with those with preserved kidney function. These data call into question proposals for higher NT-proBNP references ranges in people with CKD, and suggest that reduced kidney function per se should not be a reason to disregard higher NT-proBNP levels.
Authors
- Inder S. Anand (ORCID: https://orcid.org/0000-0003-1308-4963)
- Brian Lee Claggett (ORCID: https://orcid.org/0000-0002-4215-9218)
- Brendon Lange Neuen (ORCID: https://orcid.org/0000-0001-9276-8380)
- Finnian R. Mc Causland (ORCID: https://orcid.org/0000-0002-0299-0533)
- John J.V. McMurray (ORCID: https://orcid.org/0000-0002-6317-3975)
- Hicham Skali (ORCID: https://orcid.org/0000-0002-5629-4138)
- Marc A. Pfeffer (ORCID: https://orcid.org/0000-0003-3876-7568)
- Iris E. Beldhuis (ORCID: https://orcid.org/0000-0002-3679-168X)
- Michael R. Zile (ORCID: https://orcid.org/0000-0001-7076-221X)
- Scott David Solomon (ORCID: https://orcid.org/0000-0003-3698-9597)
- Martina M. McGrath (ORCID: https://orcid.org/0000-0001-6210-9341)
- Muthiah Vaduganathan (ORCID: https://orcid.org/0000-0003-0885-1953)
- Peder Langeland Myhre (ORCID: https://orcid.org/0000-0002-5871-1804)
- Akshay S. Desai (ORCID: https://orcid.org/0000-0002-1443-0701)
Institutions
- Brigham and Women's Hospital (US)
- University of Minnesota (US)
- University Medical Center Groningen (NL)
- Harvard University (US)
- Royal North Shore Hospital (AU)
- Akershus University Hospital (NO)
- British Heart Foundation (GB)
- The George Institute for Global Health (AU)
- Ralph H. Johnson VA Medical Center (US)
- Minneapolis VA Medical Center (US)
- University of Glasgow (GB)
Publication Details
- Journal
- JACC Heart Failure
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1016/j.jchf.2024.08.009
- Citations
- 26
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 10.45