Cholinesterase Inhibitor Initiation Does Not Increase the Risk of Fall-Related Injury in Older Adults Treated with Beta-blockers: a self-controlled case series design
There was no substantial difference in FRI risk when initiating ChEIs among older NH residents receiving beta-blocker therapy versus periods without ChEI initiation, suggesting that there is no clinically significant pharmacodynamic drug-drug interaction between beta-blockers and ChEIs.
Authors
- Lori A. Daiello (ORCID: https://orcid.org/0000-0003-3159-8597)
- Andrew R. Zullo (ORCID: https://orcid.org/0000-0003-1673-4570)
- Kaleen N. Hayes (ORCID: https://orcid.org/0000-0002-1122-0071)
- Meghan A. Cupp (ORCID: https://orcid.org/0000-0002-9900-2799)
- Melissa R. Riester (ORCID: https://orcid.org/0000-0003-2196-0134)
- Darae Ko (ORCID: https://orcid.org/0000-0002-1174-7535)
- Sarah D. Berry (ORCID: https://orcid.org/0000-0002-3793-4187)
Institutions
- Boston University (US)
- Boston Medical Center (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Brown University (US)
- Hebrew SeniorLife (US)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2024-08-31
- DOI
- https://doi.org/10.1093/gerona/glae219
- Primary Topic
- Pharmaceutical Practices and Patient Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Aging